The LS20, LS30, and LS40 are compatible with the Playstation4 Pro. The design of the front USB ports of the PS4 Pro does not allow the USB base station to fit. We recommend using the rear USB port. If using a LAN cable, the optical cable connection may interfere depending on the size of the LAN cable strain relief. If a LAN cable must be used, you can use a USB hub or extension cable to connect the base station to the USB port.